Lipids

Joint Reaction Coordinate for Computing the Free-Energy Landscape of Pore Nucleation and Pore Expansion in Lipid Membranes
Topological transitions of membranes, such as pore formation or membrane fusion, play key roles in biology, biotechnology, and in …
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Joint Reaction Coordinate for Computing the Free-Energy Landscape of Pore Nucleation and Pore Expansion in Lipid Membranes
Computer simulations of protein–membrane systems
The interactions between proteins and membranes play critical roles in signal transduction, cell motility, and transport, and they are …
Jennifer Loschwitz, Olujide O. Olubiyi, Jochen Hub, Birgit Strodel, Chetan S Poojari
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Computer simulations of protein–membrane systems
Molecular Mechanism of Polycation-Induced Pore Formation in Biomembranes
Polycations are an attractive class of macromolecules with promising applications as drug/gene carriers and biocides. The chemical …
Neha Awasthi, Wojciech Kopec, Natalia Wilkosz, Dorota Jamróz, Jochen Hub, Maria Zatorska, Rafał Petka, Maria Nowakowska, Mariusz Kepczynski
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Molecular Mechanism of Polycation-Induced Pore Formation in Biomembranes
Probing a Continuous Polar Defect: A Reaction Coordinate for Pore Formation in Lipid Membranes
Various biophysical processes involve the formation of aqueous pores over lipid membranes, including processes of membrane fusion, …
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Probing a Continuous Polar Defect: A Reaction Coordinate for Pore Formation in Lipid Membranes
Quantifying Lateral Inhomogeneity of Cholesterol-Containing Membranes
Lateral inhomogeneity plays a critical role for many properties of cholesterol-containing membranes, yet the thermodynamic forces …
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Quantifying Lateral Inhomogeneity of Cholesterol-Containing Membranes
Large Influence of Cholesterol on Solute Partitioning into Lipid Membranes
Cholesterol plays an important role in maintaining the correct fluidity and rigidity of the plasma membrane of all animal cells, and …
Christian L. Wennberg, David van der Spoel, Jochen Hub
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Large Influence of Cholesterol on Solute Partitioning into Lipid Membranes