Defects

Equivalence of Charge Imbalance and External Electric Fields during Free Energy Calculations of Membrane Electroporation

Electric fields across lipid membranes play important roles in physiology, medicine, and biotechnology, rationalizing the wide interest …

Gari Kasparyan, Jochen Hub

Joint Reaction Coordinate for Computing the Free-Energy Landscape of Pore Nucleation and Pore Expansion in Lipid Membranes

Topological transitions of membranes, such as pore formation or membrane fusion, play key roles in biology, biotechnology, and in …

Probing a Continuous Polar Defect: A Reaction Coordinate for Pore Formation in Lipid Membranes

Various biophysical processes involve the formation of aqueous pores over lipid membranes, including processes of membrane fusion, …

Jochen Hub, Neha Awasthi