Crystal structure

Structural Determinants of Phosphopeptide Binding to the N-Terminal Src Homology 2 Domain of the SHP2 Phosphatase
SH2 domain-containing tyrosine phosphatase 2 (SHP2), encoded by PTPN11, plays a fundamental role in the modulation of several signaling …
Massimiliano Anselmi, Paolo Calligari, Jochen Hub, Marco Tartaglia, Gianfranco Bocchinfuso, Lorenzo Stella
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Structural Determinants of Phosphopeptide Binding to the N-Terminal Src Homology 2 Domain of the SHP2 Phosphatase