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Massimiliano Anselmi
Postdoc
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Atomistic ensemble of active SHP2
Revealing Allostery in PTPN11 SH2 Domains from MD Simulations
Experiment-guided molecular simulations define a heterogeneous structural ensemble for the PTPN11 tandem SH2 domains
The loops of the N-SH2 binding cleft do not serve as allosteric switch in SHP2 activation
An allosteric interaction controls the activation mechanism of SHP2 tyrosine phosphatase
Structural Determinants of Phosphopeptide Binding to the N-Terminal Src Homology 2 Domain of the SHP2 Phosphatase
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